🎓 Join Our Lab

To the frontier of
lipid biology, together

We welcome graduate students (Master’s and PhD) with a clear sense of purpose who engage proactively with research. Centered on phosphoinositides, in a setting that tackles the fundamental principles of cancer, inflammatory diseases, neurodegenerative diseases, and aging, let’s grow into researchers who can communicate with the world.

At the institute we are the Department of Biochemical Pathophysiology, and we accept graduate students through the Department of Lipid Biology / Department of Cellular and Molecular Medicine at the graduate school.

Lab highlights

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Original research themes

We carry out internationally leading research in the medicine and biology of phosphoinositides and intractable diseases.

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Advanced research infrastructure

Leveraging the environment of a University for International Research Excellence and the Medical Research Laboratory, you can pursue research using cutting-edge analytical technologies.

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A strong educational system

Through progress reports, project presentations, and hands-on instruction, you steadily acquire research skills.

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An open research environment

There are many opportunities for international collaboration, and we support English communication and presentations at conferences.

Why Our Lab

Reasons to choose our lab

We provide an environment where students with scientific curiosity and passion can pose their own questions and grow into researchers who can communicate with the world.

01

Original topic setting

Lipid biology is a field with great room to approach unexplained biological phenomena. Without being bound by short-term papers, you get the chance to aim for the world’s first discoveries.

02

Research linked to drug discovery and medicine

We tackle from the fundamentals topics of great social impact — cancer, inflammatory diseases, neurodegenerative diseases, and aging. You can feel the reward of your research connecting to future medicine.

03

Diverse approaches

From biochemistry, cell biology, structural biology, and mouse experiments to the use of AI and robots, you acquire broad expertise. Practicing multifaceted approaches to a single question builds your strength as a researcher.

04

A track record of papers, talks, and awards

Our graduate students have received many conference awards, and we have a rich record of publications in top journals such as Nature, Cell, Science, and their sister journals.

05

Career development support

We have a strong record of acceptance into graduate-student support programs such as JSPS Research Fellowships, the SPRING program for next-generation researchers, and the Clinician-Scientist Development Program.

06

An atmosphere of equal discussion

Without being constrained by the teacher–student distinction, we face one another as fellow researchers. We build logical, data-based discussions and welcome ideas grounded in students’ free thinking.

Daily life in the lab

An introduction to the daily activities and atmosphere of the lab.

📅 Weekly schedule

  • Mon: Progress reports
  • Tue: Student–faculty individual consultations (as needed)
  • Wed: English class & journal club (The Cell)
  • Thu: MRL progress meeting (monthly)
  • Fri: Campus seminars (irregular)
  • Sat / Sun: No official events

🌐 Opportunities for research exchange

As your research progresses, you have opportunities to present at conferences in Japan and abroad. Through presentations and Q&A in Japanese and English, you develop the communication skills demanded of researchers and of future leaders in society. Collaboration with overseas labs is active, and we support visits and short-term study at labs in Japan and abroad. You can also routinely attend lectures by leading researchers.

🛠️ Skills you can acquire

  • Lipid profiling by mass spectrometry and chromatography
  • Omics analysis (genome, transcriptome, proteome, etc.)
  • Protein purification and in vitro enzyme assays
  • Fluorescence microscopy and live-cell imaging
  • Generation and functional analysis of genetically modified cells
  • Mouse experiments, behavioral analysis, histological and anatomical analysis
  • Lipid and omics data analysis using AI and machine learning
  • Automation and high-throughput analysis using laboratory robots

🎉 Events

We hold lab trips, welcome and farewell parties, and other social occasions. At the institute level there are beer gardens, bowling tournaments, year-end parties, and more, giving opportunities to mingle with students and faculty from other fields. Through the English class and journal club, we also value places to absorb knowledge beyond your specialty and to express your own ideas.

Admission Policy

The students we seek

The Department of Lipid Biology welcomes diligent students with a strong motivation to learn and to do research.

Strong interest and sense of purpose

Strong curiosity about the life sciences, medicine, and pharmacy, with clear goals and the motivation to engage proactively with related problems.

Foundational knowledge and skills to do research

The motivation to acquire sufficient foundational knowledge and skills to independently carry out research toward solving these problems.

Collaboration and international communication

The motivation to acquire the ethics, English ability, and communication skills needed to advance research with others and disseminate the results widely to the world.

Reference: Admission Policy, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo →

Admissions

About graduate admissions

If you wish to enter the Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, please refer to the information below. Always confirm details on the official graduate-school website.

🎓 Master’s program (M1–M2)

Graduate school / major
Graduate School of Medical and Dental Sciences, Health Sciences and Biomedical Engineering (Master’s, 2 years)
Exam timing
Usually held in summer. Additional rounds may be offered; please check the application guidelines for the year.
Eligibility
University graduates (including those expected to graduate) or those recognized by the Institute as having equivalent or higher academic ability.
Degree awarded
Master’s degree (in Medical Science, Dental Science, Oral Health, Science, Engineering, or Health Sciences)
Before applying, you must meet with the supervising faculty member of your desired field and obtain permission to apply by email.
We actively welcome applicants from other universities and faculties — science, pharmacy, agriculture, engineering, and more. Please feel free to contact us first.

🎓 Doctoral program (D1–D4)

Graduate school / major
Graduate School of Medical and Dental Sciences
· Medical and Dental Sciences (PhD, 4 years)
· Life Science, Technology and Medical Science (PhD, 3 years)
Exam timing
Usually there are first and second application rounds.
* Please check the application guidelines for the year for details.
Eligibility
Medical and Dental Sciences: Graduates of medicine, dentistry, 6-year pharmacy, or veterinary programs; holders of a master’s degree; or those recognized by the Institute as having equivalent or higher academic ability.
Life Science, Technology and Medical Science: Holders of a master’s or professional degree, or those recognized by the Institute as having equivalent or higher academic ability.
* In all cases, those expected to qualify are included.
Degree awarded
Medical and Dental Sciences: PhD (in Medicine, Dentistry, Mathematical Medical Science, or Academic studies)
Life Science, Technology and Medical Science: PhD (in Science, Engineering, Health Sciences, or Oral Health)
Before applying, you must meet with the supervising faculty member of your desired field and obtain permission to apply by email.
We actively welcome applicants from other universities and faculties — science, pharmacy, agriculture, engineering, and more. Please feel free to contact us first.
MD-PhD (Early Training for Medical Researchers) course
We also support an early-training course for medical researchers, for students of our School of Medicine. After completing the 4th or 5th year, you can advance early into the PhD program and, after obtaining a PhD (Medicine), return to the medical program. Medical students who wish to take on serious research early are welcome to consult us.
How it works

From lab visit to admission

An overview of the general flow from visit to exam to admission. Please feel free to contact us by email.

1

Email us in advance

First, email the PI (Takehiko Sasaki). Briefly tell us about yourself, your research interests, your goals for graduate study, and your preferred timing. The contact details are in the “Contact” section below.

2

Lab visit and interview

Visit the lab in person and meet with the PI and staff. You can directly check the research themes, daily lab life, and student living environment. Senior students will show you around the facilities. Online options are available for those far away in Japan or abroad.

3

Prepare for the entrance exam

Check the exam schedule, application documents, and exam subjects, and prepare. We can advise on past exams and references as needed.

4

Entrance exam and admission

Take the Institute of Science Tokyo graduate entrance exam. Please check the official graduate-school page for exam details.

5

Lab assignment and start of research

After enrolling, you decide your research theme in consultation with your supervisor. In addition to joining existing projects, you can also take on your own original theme.

FAQ

Frequently asked questions

Common questions from those considering graduate study.

I’m from another university or faculty — can I join the lab?
Yes, we welcome you. Regardless of your faculty or major, we value a sense of purpose and initiative toward research and a basic interest in the life sciences. You can acquire the necessary knowledge and skills step by step as your research progresses.
Should I visit the lab before enrolling?
If possible, we recommend visiting beforehand. Checking the lab atmosphere directly helps prevent a mismatch after enrollment. During a visit, you can also get past-exam files and advice on exam preparation from current students. Online meetings are available for those far away. Please contact us first by email.
Is there support for research funding or scholarships?
We actively support applications to programs such as JSPS Research Fellowships, the SPRING program for next-generation researchers, and the Clinician-Scientist Development Program. You can also consult us about Institute of Science Tokyo scholarship and tuition-waiver systems depending on your situation after enrolling.
Is it okay if my Japanese isn’t very good?
Yes. Perfect Japanese is not required to join the lab. We can communicate in English. You can also build up your Japanese gradually as your research and daily life in the lab progress.
Can I find a job after completing the Master’s?
Yes. Some students focus intensively on research during the Master’s, enjoy a fulfilling research life, and then find employment. Among those who completed the Master’s, some achieved excellent research results and received conference awards while enrolled.
Can physicians or dentists join the lab?
Yes, we welcome you. Our lab includes graduate students aiming to become clinician-scientists. It is well suited to those who want to learn basic research seriously while aiming to bridge to the clinic in the future. We also pursue collaborations with clinical researchers inside and outside the university, so if you are interested in both basic research and the clinic, please consult us.

Get in touch

Interested in the lab?
For visit requests, questions, or anything else — however small — please feel free to email us.

📧 Contact by email

Please contact the PI, Takehiko Sasaki, directly.
sasaki.t.7eda [at] m.isct.ac.jp
* Replace [at] with @

🏛️ Address

Medical Research Laboratory, Institute of Science Tokyo
1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan
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